Researchers have found many and varied applications for Penn-Century aerosol devices. Below are some of the main categories of use that are supported by extensive publications. Don’t be afraid to imagine new possibilities. If you develop a new area of research, please contact us. We would be happy to learn about it.
Examples of research applications
Penn-Century liquid and dry powder drug delivery devices have been used to administer:
- Pharmaceuticals – including patented and novel small molecule formulations
- Biologics – DNA and siRNA, proteins, peptides, hormones, monoclonal antibodies, surfactant
- Gene therapies – viral, non-viral and lenti-viral formulations
- Viral, bacterial infectious, or inflammatory materials – for robust disease models
- Antiobiotics
- Chemotherapies
- Bronchodilators
- Anti-fungal agents
- Cardio-pulmonary therapeutics
- Nanoparticle dry powder and liquid solutions/suspensions
- Imaging agents – dye, radio-opaque solutions and powders, fluorescent beads
- Toxicology studies – environmental or occupational hazards, biowarfare agents
- Dry powder analysis – to scan, assess particle behavior, deposition, time of flight, etc.
- In vitro uses – exposure to cells, scanning devices, cascade impactors, etc.
From fundamental research to novel therapies
Penn-Century devices have been used to better understand underlying disease processes and to develop more effective treatments for a wide range of human and veterinary diseases, including:
- Aspergillosis
- Asthma
- Biowarfare agents
- Bone Loss
- Broncheactesis
- COPD/ Emphysema
- Cystic Fibrosis
- Diabetes
- Idiopathic Pulmonary Fibrosis
- Infant or Adult Respiratory Distress Syndrome (ARDS)
- Influenza
- Lung cancer
- Pneumonia
- Pseudomonas aeruginosa
- Pulmonary Arterial Hypertension
- Sexually Transmitted Diseases
- Tuberculosis