Researchers have found many and varied applications for Penn-Century aerosol devices. Below are some of the main categories of use that are supported by extensive publications. Don’t be afraid to imagine new possibilities. If you develop a new area of research, please contact us. We would be happy to learn about it.

Examples of research applications

Penn-Century liquid and dry powder drug delivery devices have been used to administer:

  • Pharmaceuticals – including patented and novel small molecule formulations
  • Biologics – DNA and siRNA, proteins, peptides, hormones, monoclonal antibodies, surfactant
  • Gene therapies – viral, non-viral and lenti-viral formulations
  • Viral, bacterial infectious, or inflammatory materials – for robust disease models
  • Antiobiotics
  • Chemotherapies
  • Bronchodilators
  • Anti-fungal agents
  • Cardio-pulmonary therapeutics
  • Nanoparticle dry powder and liquid solutions/suspensions
  • Imaging agents – dye, radio-opaque solutions and powders, fluorescent beads
  • Toxicology studies – environmental or occupational hazards, biowarfare agents
  • Dry powder analysis – to scan, assess particle behavior, deposition, time of flight, etc.
  • In vitro uses – exposure to cells, scanning devices, cascade impactors, etc.

From fundamental research to novel therapies

Penn-Century devices have been used to better understand underlying disease processes and to develop more effective treatments for a wide range of human and veterinary diseases, including:

  • Aspergillosis
  • Asthma
  • Biowarfare agents
  • Bone Loss
  • Broncheactesis
  • COPD/ Emphysema
  • Cystic Fibrosis
  • Diabetes
  • Idiopathic Pulmonary Fibrosis
  • Infant or Adult Respiratory Distress Syndrome (ARDS)
  • Influenza
  • Lung cancer
  • Pneumonia
  • Pseudomonas aeruginosa
  • Pulmonary Arterial Hypertension
  • Sexually Transmitted Diseases
  • Tuberculosis